Cancer incidence after cholecystectomy--a cohort study with 30 years follow-up.
Cancer incidence after cholecystectomy--a cohort study with 30 years follow-up.
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胆囊切除术后癌症发生率——一项跟踪 30 年的队列研究。
DOI：
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发表时间：
1989
期刊：
影响因子：
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通讯作者：
H. Olsson
中科院分区：
文献类型：
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作者：
S. Gudmundsson;T. Möller;H. Olsson
霍乱与结肠直肠癌、乳腺癌和生殖系统癌症的增加有关。本文对1951 ~ 1955年胆囊切除术后472例病人（女398例，男74例）的癌发生率进行了调查。我们的研究结果显示，女性组乳腺癌的风险增加（P = 0.016），但结直肠癌或妇科癌的风险没有显着增加。术后患乳腺癌的风险随时间的延长而增加。在我们的一小组男性中，结肠癌的SMR升高，但没有达到统计学显著性。胆囊切除术和乳腺癌之间的关联可能的病因因素进行了讨论。
Cholecystectomy has been connected with an increase in colorectal, breast and reproductive system cancers. On 472 patients, 398 women and 74 men, cholecystectomized during the years 1951 to 1955, cancer incidence was investigated. Our results show an elevated risk of breast cancer in the female group (P = 0.016), but no significant increased risk in colorectal or gynaecologic cancer. The risk for breast cancer increased with time after operation. In our small group of men an elevated SMR was noted for colon cancer without reaching statistical significance. Possible aetiological factors for the association between cholecystectomy and breast cancer are discussed.