VARIABILITY OF HEART-RATE, P-R, QRS AND Q-T DURATIONS IN TWINS

VARIABILITY OF HEART-RATE, P-R, QRS AND Q-T DURATIONS IN TWINS
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DOI:
10.1016/s0022-0736(80)80008-2
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发表时间:
1980-01-01
影响因子:
1.3
通讯作者:
FEINLEIB, M
FEINLEIB, M
中科院分区:
医学4区
文献类型:
--
作者:
HAVLIK, RJ;GARRISON, RJ;FEINLEIB, M

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在一项心血管危险因素研究中,对 355 组中年男性同卵双胞胎和异卵双胞胎进行了心电图检查。使用经典统计孪生方法研究了心室率和 R-R、QRS 和 Q-T 持续时间的潜在遗传变异性。心室率和 P-R 间期存在显着的遗传变异性。显然,心率和心房除极(在较小程度上)均受到遗传控制,其中 54% 和 34% 的个体间差异可通过遗传来解释。
During a cardiovascular risk factor study ECG were done on 355 sets of middle-aged male monozygotic and dizygotic twins. Potential genetic variability in ventricular rate and R-R, QRS and Q-T duration was investigated using classical statistical twin methodology. Significant genetically determined variability was found for ventricular rate and P-R interval. Apparently, heart rate and, to a lesser extent, atrial depolarization are under genetic control with 54% and 34%, respectively, of the variation among individuals explained by heredity.