INTRACELLULAR-RECORDINGS FROM COCHLEAR OUTER HAIR-CELLS
INTRACELLULAR-RECORDINGS FROM COCHLEAR OUTER HAIR-CELLS
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DOI：
10.1126/science.7123260
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发表时间：
1982-01-01
期刊：
影响因子：
56.9
通讯作者：
FLOCK, A
中科院分区：
文献类型：
--
作者：
DALLOS, P;SANTOS-SACCHI, J;FLOCK, A
对豚鼠耳蜗第3回的外毛细胞进行细胞内记录，并与同一记录区的内毛细胞、支持细胞和细胞外间隙的电特性进行比较。外毛细胞的膜电位高于内毛细胞，但它们产生的AC受体电位较小。这两种毛细胞的频率响应特性可能没有显著差异。在调谐最佳的频率区域，两种类型的细胞都会产生去极化的DC受体电位，但外毛细胞也会在低频率下产生超极化反应。
Intracellular recordings were made from outer hair cells in the 3rd turn of the guinea pig cochlea, and the electrical characteristics of the cells were compared to those of inner hair cells, supporting cells, and extracellular spaces from the same recording region. Outer hair cells have higher membrane potentials than do inner hair cells, but they produce smaller AC receptor potentials. The frequency response characteristics of both types of hair cells are probably not significantly different. In the frequency region where tuning is optimal, both cell types produce depolarizing DC receptor potentials, but outer hair cells also generate hyperpolarizing responses at low frequencies.