Epstein-Barr virus-associated peripheral T-cell lymphoma in adults with hydroa vacciniforme-like lesions
Epstein-Barr virus-associated peripheral T-cell lymphoma in adults with hydroa vacciniforme-like lesions
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DOI：
10.1046/j.1365-2230.2001.00805.x
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发表时间：
2001-05-01
影响因子：
4.1
通讯作者：
Han, WS
中科院分区：
文献类型：
--
作者：
Cho, KH;Kim, CW;Han, WS
我们描述了两名韩国成年患者谁坏死丘疹主要是在他们的脸上。皮肤活检标本显示血管周围和附件周围浸润的非典型淋巴细胞与血管炎的真皮和皮下组织。原位杂交表明，真皮中的大部分淋巴细胞中存在EB病毒的潜伏感染。这些患者被诊断为T细胞淋巴瘤。有趣的是，在病例2的外周血中发现了大颗粒淋巴细胞增多症。
We describe two Korean adult patients who had necrotizing papulovesicles mainly on their faces. Skin biopsy specimens showed perivascular and periadnexal infiltrate of atypical lymphoid cells with vasculitis in the dermis and subcutaneous tissue. In situ hybridization demonstrated a latent infection of Epstein-Barr virus in the majoriy of lymphoid cells in the dermis. These patients were diagnosed as having T-cell lymphoma. Interestingly, large granular lymphocytosis was found in the peripheral blood of Case 2.