X-Ray-Induced Acoustic Computed Tomography (XACT): Initial Experiment on Bone Sample.
X-Ray-Induced Acoustic Computed Tomography (XACT): Initial Experiment on Bone Sample.
复制标题
DOI：
10.1109/tuffc.2020.3032779
复制
发表时间：
2021-04
期刊：
影响因子：
--
通讯作者：
Xiang L
中科院分区：
文献类型：
--
作者：
Robertson E;Samant P;Wang S;Tran T;Ji X;Xiang L
X射线诱导声计算机层析成像(XACT)是一种结合了高X射线吸收对比度和高超声分辨率的独特的混合成像方式。X射线摄影和计算机断层摄影(CT)是目前骨骼组织二维和三维成像的金标准，尽管骨的重要特性，如弹性和声速，这些技术无法测量。超声能够测量这些特性，尽管目前的临床超声扫描仪不能用来对骨骼的内部形态进行成像，因为它们无法解决精确图像重建所涉及的复杂物理问题；骨骼是异质的，由皮质和松质骨层组成，这违反了传统超声成像中关于等声速的假设。XACT与时间反转算法相结合，能够产生精确的重建结果，并且通过结合X射线和超声波成像的元素，XACT有可能在低辐射剂量下比任何一种技术获得更多的信息。本文重点介绍了通过超声换能器的线性扫描和时间反转算法来产生第一个骨样本的XACT图像的X射线诱导声检测。这项研究的结果应该被证明增强XACT成像在未来临床应用中评估骨疾病的潜力。
X-ray induced acoustic computed tomography (XACT) is a unique hybrid imaging modality that combines high X-ray absorption contrast with high ultrasonic resolution. X-ray radiography and computerized tomography (CT) are currently the gold standards for two-dimensional and three-dimensional imaging of skeletal tissues, though there are important properties of bone, such as elasticity and speed of sound, that these techniques cannot measure. Ultrasound is capable of measuring such properties, though current clinical ultrasound scanners cannot be used to image the interior morphology of bones because they fail to address the complicated physics involved for exact image reconstruction; bone is heterogeneous and composed of layers of both cortical and trabecular bone, which violates assumptions in conventional ultrasound imaging of uniform speed of sound. XACT, in conjunction with the time-reversal algorithm, is capable of generating precise reconstructions, and, by combining elements of both X-ray and ultrasound imaging, XACT is potentially capable of obtaining more information than any single of these techniques at low radiation dose. This paper highlights X-ray-induced acoustic detection through linear scanning of an ultrasound transducer and the time-reversal algorithm to produce the first-ever XACT image of a bone sample. Results of this study should prove to enhance the potential of XACT imaging in the evaluation of bone diseases for future clinical use.