DISTRIBUTIONS OF CARDIOPULMONARY VARIABLES IN PEDIATRIC SURVIVORS AND NONSURVIVORS OF SEPTIC SHOCK
DISTRIBUTIONS OF CARDIOPULMONARY VARIABLES IN PEDIATRIC SURVIVORS AND NONSURVIVORS OF SEPTIC SHOCK
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DOI：
10.1097/00003246-198506000-00002
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发表时间：
1985-01-01
影响因子：
8.8
通讯作者：
RUTTIMANN, UE
中科院分区：
文献类型：
--
作者：
POLLACK, MM;FIELDS, AI;RUTTIMANN, UE
在42例感染性休克患儿（18例存活）中研究了心肺变量与预后的关系。在主动BP支持期间获得所有心肺变量。通过两种经验性截断方法将变量分布分为范围：正常范围和存活者中位数。楔压和心脏指数正常的存活者比例显著高于对照组（P<. 05)高于正常范围外的幸存者比例。生存率也有显著性差异（p<. 05)氧耗量、动静脉氧含量差、氧提取率、pH值和核心温度高于正常值时，有显著性差异（P<. 05)楔压、肺分流和pH值低于存活者中位数的死亡率较高。基于这八个变量的分布的治疗目标隔离患者组的生存率为59%至75%，相比之下，总生存率为43%。
The association of cardiopulmonary variables with outcome was investigated in 42 pediatric patients (18 survivors) with septic shock. All cardiopulmonary variables were obtained during active BP support. The variable distributions were separated into ranges by two empiric cutoff methods: normal ranges and the survivor median values. The proportion of survivors with normal values of wedge pressure and cardiac index was significantly (p<. 05) higher than the proportion of survivors outside the normal range. The percentage of survival also significantly (p<. 05) increased with above-normal values of oxygen consumption, arteriovenous O 2 content difference, O 2 extraction, pH, and core temperature. There were significantly (p<. 05) more nonsurvivors with wedge pressure, pulmonary shunt, and pH values below the survivor medians. Therapeutic goals based on the distributions of these eight variables isolated patient groups with survival rates of 59% to 75%, compared to the overall survival rate of 43%.