Pain and Functional Status in Patients With Ventricular Assist Devices.
Pain and Functional Status in Patients With Ventricular Assist Devices.
复制标题
使用心室辅助装置的患者的疼痛和功能状态。
DOI：
10.1016/j.jpainsymman.2016.05.016
复制
发表时间：
2016
影响因子：
4.7
通讯作者：
Ascheim,DeborahD
中科院分区：
文献类型：
--
作者：
Weerahandi,Himali;Goldstein,Nathan;Gelfman,LauraP;Jorde,Ulrich;Kirkpatrick,JamesN;Marble,Judith;Naka,Yoshifumi;Pinney,Sean;Slaughter,MarkS;Bagiella,Emilia;Ascheim,DeborahD
目的本研究考察了VAD患者疼痛、功能状态和生活质量随时间的变化。方法患者在植入VAD之前或之后尽可能早地进行前瞻性队列研究，然后进行长达48周的随访。使用简明的疼痛问卷评估疼痛。采用Katz日常生活独立能力问卷评定患者的功能状态。采用堪萨斯城心肌病问卷，包括身体功能、症状、社会功能、自我效能感和生活质量5个领域的23个项目的问卷，用于评估患者的生活质量和健康状况。植入前和植入后48周的疼痛严重程度评分中位数分别为2.8(四分位数范围0.5~5.0)和0.0(四分位数范围0.0~5.3)(P=0.0.0009)。随着时间的推移，卡茨日常生活独立活动总结得分也显示出显著的改善(P<；0.0001)。堪萨斯城心肌病问卷摘要量表显示随着时间的推移有显著的改善(P<；0.0016)。结论这项研究表明，随着时间的推移，VADS患者的疼痛、功能状态和生活质量都有所改善。这些数据可能有助于患者在考虑接受VAD植入时做出决定。
ContextVentricular assist devices (VADs) have been shown to improve survival and overall quality of life, but there are limited data on pain control and functional status in this patient population.ObjectivesThis study examined changes in pain, functional status, and quality of life over time in VAD patients.MethodsPatients were enrolled in this prospective cohort study before or as early after VAD implant as possible and then followed for up to 48 weeks. The Brief Pain Inventory was used to assess pain. The Katz Independent Activities of Daily Living questionnaire was used to assess functional status. The Kansas City Cardiomyopathy Questionnaire, a 23-item questionnaire covering five domains (physical function, symptoms, social function, self-efficacy, and quality of life), was used to assess quality of life and health status.ResultsEighty-seven patients were enrolled at four medical centers. The median Brief Pain Inventory severity score was 2.8 (interquartile range 0.5–5.0) before implantation and 0.0 (interquartile range 0.0–5.3) 48 weeks after implantation (P= 0.0009). Katz Independent Activities of Daily Living summary scores also demonstrated significant improvement over time (P< 0.0001). Kansas City Cardiomyopathy Questionnaire summary scales demonstrated significant improvement with time (P< 0.0016).ConclusionThis study demonstrated that patients with VADs experienced improved pain, functional status, and quality of life over time. These data may be useful to help patients make decisions when they are considering undergoing VAD implantation.