An 18-Year Follow-Up of Patients Admitted to Methadone Treatment for the First Time
An 18-Year Follow-Up of Patients Admitted to Methadone Treatment for the First Time
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DOI：
10.1080/10550880802544997
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发表时间：
2009-01-01
影响因子：
2.3
通讯作者：
Romelsjo, Anders
中科院分区：
文献类型：
--
作者：
Davstad, Ingrid;Stenbacka, Marlene;Romelsjo, Anders
1985 年至 2003 年的 18 年成瘾生涯中，有 157 名海洛因依赖者（73% 为男性；49% 人类免疫缺陷病毒血清阳性）在 1989 年至 1991 年期间首次接受斯德哥尔摩美沙酮维持治疗计划，并使用来自七个官方登记册和患者记录的数据进行了分析。在观察期结束时计算第一次美沙酮维持治疗、第一次美沙酮维持治疗出院、第二次美沙酮维持治疗和第二次美沙酮维持治疗出院的受试者的回归分析和各种结果的发生率。人类免疫缺陷病毒呈阳性（HR = 3.8）、住宿（HR = 1.9）和监禁（HR = 1.7）预计45%的死者将死亡。大约 70% 的在世受试者每年都会在某个时期参加美沙酮维持治疗。与第一次或第二次美沙酮维持治疗出院的受试者 (50%) 相比，接受第一次或第二次美沙酮维持治疗的受试者犯罪率较低，且接受美沙酮维持治疗的时间更长 (70% 至 100%)。对于问题严重程度较高的患者，应加强努力和干预，以增加治疗时间。
An 18-year addiction career, 1985-2003, for 157 heroin dependent subjects (73% men; 49% human immunodeficiency virus seropositive) admitted for the first time to Stockholm's Methadone Maintenance Treatment program during 1989 to 1991 was analyzed with data from seven official registers and patient records. Regression analyses and incidence rates for various outcomes were calculated for subjects in first methadone maintenance treatment at the end of the observation period, discharged from first methadone maintenance treatment, in second methadone maintenance treatment, and discharged from second methadone maintenance treatment. Being human immunodeficiency virus positive (HR = 3.8), lodging (HR = 1.9) and prison sentence (HR = 1.7) predicted mortality for the 45% deceased. Approximately 70% of living subjects participated in methadone maintenance treatment at some period each year. Subjects in first or second methadone maintenance treatment had less criminality and had spent more time in methadone maintenance treatment (70% to 100%) than those discharged from first or from second methadone maintenance treatment (50%). Efforts and interventions should be intensified to increase time in treatment also for those with high problem severity.