Synthesis of the putative structure of eupomatilone-6
Synthesis of the putative structure of eupomatilone-6
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DOI：
10.1021/ol035908j
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发表时间：
2004-02-05
期刊：
影响因子：
5.2
通讯作者：
Ramana, CV
中科院分区：
文献类型：
--
作者：
Gurjar, MK;Cherian, J;Ramana, CV
通过Suzuki偶联、Sharpless不对称双羟基化和分子内Horner-Wadsworth-Emmons反应合成了eupomatilone-6（1）。对合成的eupomatilone-6进行的光谱研究与报道的天然产物不一致，因此需要对指定结构进行修订。
The synthesis of eupomatilone-6 (1) has been achieved by using Suzuki coupling, Sharpless asymmetric dihydroxylation, and intramolecular Horner-Wadsworth-Emmons reactions. The spectroscopic studies carried out on synthetic eupomatilone-6 do not agree with those reported for the natural product, and therefore revision of the assigned structure is warranted.