Some aspects of optimization of an invasive microwave antenna for local hyperthermia treatment of cancer.
Some aspects of optimization of an invasive microwave antenna for local hyperthermia treatment of cancer.
复制标题
用于癌症局部热疗治疗的侵入式微波天线优化的某些方面。
DOI：
10.1118/1.594930
复制
发表时间：
1981
期刊：
影响因子：
3.8
通讯作者：
Trembly,BS
中科院分区：
文献类型：
--
作者：
deSieyes,DC;Douple,EB;Strohbehn,JW;Trembly,BS
热疗已经成为其他形式癌症治疗的一种有前途的替代或辅助疗法。为了利用浸入重要正常组织区域的局部热疗，研制了一种侵入式微波同轴单极子天线。采用了一种实验方法来表征和优化嵌入在组织等效模和狗脑中的裸露和绝缘天线的电磁特性和加热能力。四种方法被用来显示微波探头的热分布：液晶技术，凝胶技术，以及用热敏电阻探头直接在体模和狗脑中测量温度。研究的参数包括：天线阻抗、插入深度、天线绝缘(介电常数和厚度)、轴绝缘和频率。
Hyperthermia has emerged as a promising alternative or adjunct to other forms of cancer therapy. In order to utilize hyperthermia in very localized volumes immersed in regions of vital normal tissue, an invasive microwave coaxial monopole antenna has been developed. An experimental approach has been taken to characterize and optimize the electromagnetic properties and heating capabilities of bare and insulated antennas imbedded in tissue equivalent phantoms and dog brain. Four methods have been used to visualize the thermal profiles of the microwave probes: the liquid crystal technique, the gelatin technique, and the direct measurement of temperature with thermistor probes in phantom and dog brain. Among the parameters studied are: antenna impedance, insertion depth, antenna insulation (dielectric constant and thickness), shaft insulation, and frequency.