Detection of consensuses and treatment principles of diabetic nephropathy in traditional Chinese medicine: A new approach
Detection of consensuses and treatment principles of diabetic nephropathy in traditional Chinese medicine: A new approach
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DOI：
10.1016/j.jtcms.2016.02.001
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发表时间：
2015-10
影响因子：
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通讯作者：
Xu Tong;Qingyu Xie;Guang Rong;Sheng Zhou;Qinggang Meng
中科院分区：
文献类型：
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作者：
Xu Tong;Qingyu Xie;Guang Rong;Sheng Zhou;Qinggang Meng
目的提出并验证一种在社会计算领域基于群落检测的揭示中医药共识和治疗原则的新方法。方法检索3个中文数据库(CNKI、VIP和万方数据)，检索从糖尿病肾病(DN)成立至2014年9月31日的中医药治疗文献。从收录文献中提取中医辨证论治数据，构建糖尿病肾病中医辨证论治网络(DNZCT)，节点表示中医证候，边表示中医辨证论治关系。结果构建了一个由201个节点和743条边组成的网络，检测到6个社区。聚在同一社区的节点捕捉到了相同的语义主题；不同的社区具有独特的特征，并表明了不同的处理原则。结论基于群落检测的方法在揭示中医对糖尿病肾病治疗的共识和治疗原则方面是有用和可行的，并可用于解决其他类似的中医问题。
ObjectiveTo propose and test a new approach based on community detection in the field of social computing for uncovering consensuses and treatment principles in traditional Chinese medicine (TCM).MethodsThree Chinese databases (CNKI, VIP, and Wan Fang Data) were searched for published articles on TCM treatment of diabetic nephropathy (DN) from their inception until September 31, 2014. Zheng classification and herb data were extracted from included articles and used to construct a Zheng classification and treatment of diabetic nephropathy (DNZCT) network with nodes denoting Zhengs and herbs and edges denoting corresponding treating relationships among them. Community detection was applied to the DNZCT and detected community structures were analyzed.ResultsA network of 201 nodes and 743 edges were constructed and six communities were detected. Nodes clustered in the same community captured the same semantic topic; different communities had unique characteristics, and indicated different treatment principles. Large communities usually represented similar points of view or consensuses on common Zheng diagnoses and herb prescriptions; small communities might help to indicate unusual Zhengs and herbs.ConclusionThe results suggest that the community detection-based approach is useful and feasible for uncovering consensuses and treatment principles of DN treatment in TCM, and could be used to address other similar problems in TCM.