Twelve-year review of recurrent native-valve infective endocarditis: a disease of the modern antibiotic era.
Twelve-year review of recurrent native-valve infective endocarditis: a disease of the modern antibiotic era.
复制标题
复发性自体瓣膜感染性心内膜炎十二年回顾：现代抗生素时代的一种疾病。
DOI：
10.1093/clinids/10.6.1163
复制
发表时间：
1988
期刊：
影响因子：
--
通讯作者：
Larry M. Baddour
中科院分区：
文献类型：
--
作者：
Larry M. Baddour
仅在过去的四十年中，才发现了自体瓣膜心内膜炎的复发病例。在回顾过去12年的英文文献中，发现了281例复发性感染性心内膜炎病例，男性比女性多三倍。静脉注射药物是43%患者心内膜炎的指定危险因素。与有其他心内膜炎危险因素的患者相比，静脉注射药物的患者在原发性（或既往）心内膜炎发作后12个月内复发的可能性更大（P <0.005）。从复发性心内膜炎患者中分离出的微生物种类多于原发性心内膜炎患者。原发性和复发性感染的瓣膜受累在主动脉瓣、二尖瓣和三尖瓣之间分布均匀。虽然复发性自体瓣膜心内膜炎的并发症相对常见，但与复发相关的死亡率低于30%。
Recurrent cases of native-valve endocarditis have been seen for only the past four decades. In a review of the English-language literature over the past 12 years, 281 cases of recurrent infective endocarditis were found. Males were more than three times more commonly identified than females. Intravenous drug use was a designated risk factor for endocarditis in 43% of patients. Compared with patients with other risk factors for endocarditis, patients with intravenous drug use were significantly more likely (P less than .005) to suffer a recurrent bout of native-valve endocarditis within 12 months after the primary (or previous) episode. A greater variety of organisms were isolated from patients with recurrent endocarditis than from those with primary endocarditis. Valvular involvement was evenly distributed among the aortic, mitral, and tricuspid valves for both primary and recurrent episodes of infection. While complications of recurrent native-valve endocarditis were relatively common, the mortality rate associated with the recurrences was less than 30%.