Fluorescent x-ray computed tomography using the pinhole effect for biomedical applications
Fluorescent x-ray computed tomography using the pinhole effect for biomedical applications
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DOI：
10.1016/j.optcom.2013.01.071
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发表时间：
2013-06-15
影响因子：
2.4
通讯作者：
Zeniya, Tsutomu
中科院分区：
文献类型：
--
作者：
Sunaguchi, Naoki;Yuasa, Tetsuya;Zeniya, Tsutomu
我们提出了一种利用体积光束和针孔准直器有效获得三维图像的荧光x射线计算机断层扫描技术，旨在为分子成像提供可量化的测量和亚毫米空间分辨率。在这项研究中，我们证明了这一概念的可行性，并通过成像物理幻影来研究成像特性，如空间分辨率、对比度分辨率和可量化措施。在日本KEK的BLNE-7A弯曲磁束线（6.5 GeV）上构建了单色同步辐射x射线成像系统。(C) 2013 Elsevier B.V.版权所有
We propose a fluorescent x-ray computed tomography using volumetric beam and pinhole collimator to obtain 3-dimensional image effectively, aimed at providing molecular imaging with quantifiable measures and sub-millimeter spatial resolution. In this study, we demonstrate the feasibility of this concept and investigate imaging properties such as spatial resolution, contrast resolution and quantifiable measures, by imaging physical phantoms. A preliminary imaging system using monochromatic synchrotron x-rays was constructed at the BLNE-7A bending-magnet beamline (6.5 GeV) at KEK, Japan. (C) 2013 Elsevier B.V. All rights reserved.