Depression in men in the postnatal period and later child psychopathology: a population cohort study.
Depression in men in the postnatal period and later child psychopathology: a population cohort study.
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DOI：
10.1097/chi.0b013e31816429c2
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发表时间：
2008-04
影响因子：
13.3
通讯作者：
Evans J
中科院分区：
文献类型：
--
作者：
Ramchandani PG;Stein A;O'Connor TG;Heron J;Murray L;Evans J
妇女的产后抑郁症与对产妇健康和儿童发育的不利影响有关。目前尚不清楚男性抑郁症是否会造成类似的风险。本研究旨在评估男性产后抑郁症与其子女日后精神疾病之间的关系，并调查男性产后抑郁症的诱发因素。一个基于人群的队列的10,975名父亲和他们的孩子从雅芳纵向研究的父母和孩子（ALSPAC）招募在产前阶段，并随访了7年。父亲的抑郁症状进行了评估与爱丁堡产后抑郁量表，后来的儿童精神障碍（DSM-IV）与发展和幸福感评估（DAWBA）。在调整母亲抑郁和父亲教育水平后，产后父亲抑郁与7年后子女的精神障碍显著相关（调整后比值比1.72，95%置信区间1.07至2.77），最显著的是对立违抗/行为障碍（调整后OR 1.94，95%置信区间1.04至3.61）。过去的严重抑郁症的历史，高产前症状得分的抑郁症和焦虑症是最强的预测父亲抑郁症在出生后的时期。产后抑郁症的父亲与后来的精神疾病在他们的孩子，独立的母亲产后抑郁症。需要进一步研究与父亲精神病理学相关的风险，因为这可能是公共卫生干预的重要机会。
Postnatal depression in women is associated with adverse effects on both maternal health and children's development. It is unclear whether depression in men at this time poses comparable risks. The present study set out to assess the association between depression in men in the postnatal period and later psychiatric disorders in their children, and to investigate predisposing factors for depression in men following childbirth. A population based cohort of 10,975 fathers and their children from the Avon Longitudinal Study of Parents and Children (ALSPAC) were recruited in the prenatal period and followed up for 7 years. Paternal depressive symptoms were assessed with the Edinburgh Postnatal Depression Scale, and later child psychiatric disorder (DSM-IV) with the Development and Well-Being Assessment (DAWBA). Depression in fathers in the postnatal period was significantly associated with psychiatric disorder in their children 7 years later (adjusted Odds Ratio 1.72, 95% confidence interval 1.07 to 2.77), most notably oppositional-defiant/conduct disorders (adj. OR 1.94, 95% confidence interval 1.04 to 3.61), after adjusting for maternal depression and paternal educational level. A past history of severe depression, and high prenatal symptom scores for depression and anxiety were the strongest predictors of paternal depression in the postnatal period. Depression in fathers in the postnatal period is associated with later psychiatric disorders in their children, independently of maternal postnatal depression. Further research is required into the risks associated with paternal psychopathology, as this could represent an important opportunity for public health intervention.