Toxic adjuvants alter the function and phenotype of dendritic cells to initiate adaptive immune responses induced by oral Helicobacter pylori vaccines

Toxic adjuvants alter the function and phenotype of dendritic cells to initiate adaptive immune responses induced by oral Helicobacter pylori vaccines
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DOI:
10.1111/hel.12536
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发表时间:
2018-09
期刊:
影响因子:
4.4
通讯作者:
Shuanghui Luo;Wei Liu;Zhiqin Zeng;Feng Ye;Chupeng Hu;Ningyin Xu;An Huang;Tao Xi;Yingying Xing
Shuanghui Luo;Wei Liu;Zhiqin Zeng;Feng Ye;Chupeng Hu;Ningyin Xu;An Huang;Tao Xi;Yingying Xing
中科院分区:
医学2区
文献类型:
--
作者:
Shuanghui Luo;Wei Liu;Zhiqin Zeng;Feng Ye;Chupeng Hu;Ningyin Xu;An Huang;Tao Xi;Yingying Xing

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毒性佐剂被视为口服幽门螺杆菌(Hp)疫苗不可或缺的成分。然而,毒性佐剂在启动适应性免疫反应中的具体作用在很大程度上尚未得到阐释。
Toxic adjuvant is considered as an indispensable constituent for oral Helicobacter pylori (H. pylori) vaccines. However, the elaborate role of toxic adjuvant in the initiation of adaptive immune response is largely undescribed.