Enteral nutrition: potential role in regulating immune function
Enteral nutrition: potential role in regulating immune function
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肠内营养：调节免疫功能的潜在作用
DOI：
10.1097/00001574-199004000-00004
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发表时间：
1990
影响因子：
2.5
通讯作者：
J. Askanazi
中科院分区：
文献类型：
--
作者：
D. P. Katz;V. Kvetan;J. Askanazi
很多争议都集中在危重病人的肠内和肠外喂养的相对优势上。肠内营养提供了一个主要的优势，因为它易于管理和理论上的营养功效，因为营养物质被更多的“生理”清除。显然，肠内喂养最能保持肠道粘膜的完整性。最近的证据表明，肠道粘膜在免疫功能中的作用可能比迄今所知的更大，并可能为危重患者提供第一道防线。目前讨论的目的是回顾这一领域的一些最新研究和新的证据表明，肠内营养可以调节免疫功能。
Much controversy has centered on the relative advantages of enteral and parenteral feeding of the acutely ill patient. Enteral nutrition offers a major advantage, with its ease of administration and theoretical nutritional efficacy, given the more'physiological'clearance of nutrients. Clearly, the integrity of intestinal mucosa is best maintained by enteral feeding. Recent evidence suggests that the mucosa of the gut may play a greater role in immune function than was hitherto realized and may offer a first line of defense in the critically ill patient. The aim of the present discussion is to review some Of the more recent studies in this area and new evidence suggesting that immune function can be modulated by enteral nutrition.