Afferent and efferent enkephalinergic systems of the tegmental nuclei of Gudden in the rat: an immunocytochemical study
Afferent and efferent enkephalinergic systems of the tegmental nuclei of Gudden in the rat: an immunocytochemical study
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大鼠 Gudden 被盖核的传入和传出脑啡肽能系统：免疫细胞化学研究
DOI：
10.1016/0006-8993(87)90354-4
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发表时间：
1987
期刊：
影响因子：
2.9
通讯作者：
M. Tohyama
中科院分区：
文献类型：
--
作者：
M. Yamano;M. Tohyama
采用免疫细胞化学结合刀切和毁损实验，研究了大鼠Gudden腹侧被盖核（VT）内l-ENKLI纤维的传入来源及Gudden背侧被盖核（DDT）背侧部l-ENKLI结构的传出和传入联系。VT有密集的ENKLI纤维丛，但无ENKLI细胞。破坏背侧乳头体前核和内侧乳头体核内侧部，其中包含一个大组的l-ENKLI神经元，显着减少l-ENKLI纤维在同侧VT，这表明，大多数这些纤维起源于这些核。DDT中含有大量的ENKLI神经元和密集的ENKLI纤维。损毁DDT可使对侧脚间核背外侧部的l-ENKLI纤维明显减少，提示DDT内的l-ENKLI神经元向对侧脚间核投射，DDT内的l-ENKLI纤维可能是内源性的。
We studied the afferent source ofl-enkephalin-like immunoreactive (l-ENKLI) fibers in the ventral tegmental nucleus (VT) of Gudden, and efferent and afferent connections ofl-ENKLI structures in the dorsal part of the dorsl tegmental nucleus (DDT) of Gudden in the rat, using immunocytochemistry combined with knife-cut and lesion experiments. The VT had a dense plexus ofl-ENKLI fibers but nol-ENKLI cells. Destruction of the dorsal premammillary nucleus and medial mammillary nucleus pars medialis, which contained a large group ofl-ENKLI neurons, markedly reducedl-ENKLI fibers in the ipsilateral VT, suggesting that most of these fibers originate in these nuclei. The DDT contained a large collection ofl-ENKLI neurons together with densel-ENKLI fibers. Destruction of the DDT caused a contralateral marked reduction ofl-ENKLI fibers in the dorsolateral part of the interpeduncular nucleus (DL), suggesting thatl-ENKLI neurons in the DDT project contralaterally to the DL.l-ENKLI fibers in the DDT may be of intrinsic origin.
DOI：
10.1177/28.8.7003009
发表时间：
1980
期刊：
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society
影响因子：
--
作者：
Miller,RJ;Pickel,VM
通讯作者：
Pickel,VM