Usefulness of positron emission tomography-CT for diagnosis of primary bone marrow lymphoma in children
Usefulness of positron emission tomography-CT for diagnosis of primary bone marrow lymphoma in children
复制标题
正电子发射断层扫描-CT在儿童原发性骨髓淋巴瘤诊断中的应用
DOI：
10.1080/08880018.2018.1459984
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发表时间：
2018
影响因子：
1.7
通讯作者：
Nagai Kozo
中科院分区：
文献类型：
--
作者：
Moritani Kyoko;Nakano Naoko;Yonezawa Sachiko;Ochi Fumihiro;Tauchi Hisamichi;Eguchi-Ishimae Minenori;Eguchi Mariko;Ishii Eiichi;Nagai Kozo
儿童原发性骨髓淋巴瘤（PBML）由于骨髓中的恶性细胞难以识别而难以诊断。第一个病例是一名5岁男孩，表现为膝关节肿胀伴间歇性发热。第二个病例是一名12岁女孩，表现为不明原因的发热，无淋巴结病或肝脾肿大。在这两种情况下，尽管反复骨髓穿刺，但诊断未得到证实。最后，骨髓穿刺和活检阳性部位的正电子发射断层扫描（PET）-CT有助于明确诊断PBML。PET-CT对无特异性症状的儿童PBML的诊断有重要价值。
Primary bone marrow lymphoma (PBML) is hard to diagnose in children, due to the difficult identification of malignant cells in bone marrow. The first case, a 5-year-old boy, showed knee swelling with an intermittent fever. The second case, a 12-year-old girl, showed fever of unknown origin without lymphadenopathy or hepatosplenomegaly. In both cases, the diagnosis was not confirmed despite the repeated bone marrow aspirations. Finally, bone marrow aspiration and biopsy at the positive site by positron emission tomography (PET)-CT contributed to definitive diagnosis of PBML. The PET-CT is useful for the accurate diagnosis of PBML in children with non-specific symptoms.