Measurement of cartilage thickness in the human knee-joint by magnetic resonance imaging using a three-dimensional gradient-echo sequence
Measurement of cartilage thickness in the human knee-joint by magnetic resonance imaging using a three-dimensional gradient-echo sequence
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DOI：
10.1007/s002640050367
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发表时间：
1999-12-01
影响因子：
2.7
通讯作者：
Swoboda, B
中科院分区：
文献类型：
--
作者：
Kladny, B;Martus, P;Swoboda, B
我们研究了人体标本和比较数据的软骨厚度测量与磁共振成像，通过使用图像分析系统与相应的组织切片中的每个部门的中间。研究结果基于26个膝关节的768次测量。总体而言，磁共振/解剖相关性非常好（r=0.88）。最差的相关性是在股骨的部门（r=0.69）。这种相关性似乎不依赖于骨关节炎软骨病变的级别。尽管相关率良好，但平均磁共振/解剖差异（绝对值）为0.41 mm（标准差（SD）0.34 mm）或18.08%（SD 18.9%）。如果通过这种方法评估软骨厚度具有临床意义，则需要改进成像技术。
We studied human specimens and compared data on cartilage thickness measurements with magnetic resonance imaging by using an image analysing system with corresponding histological sections in the middle of each sector. The findings are based on 768 measurements in 26 knee joints. Overall, there was very good magnetic resonance/anatomic correlation (r=0.88). The poorest correlation was in the sectors of the femur (r=0.69). The correlation seemed not to be dependent on the grade of osteoarthritic cartilage lesions. Despite good correlation rates, the mean magnetic resonance/anatomic difference (absolute values) was 0.41 mm (standard deviation (SD) 0.34 mm) or 18.08% (SD 18.9%). Imaging techniques need to be improved if the assessment of cartilage thickness by this means is to be of clinical relevance.