Morphological transformation of rat embryo cells by the combined action of 3-methylcholanthrene and Rauscher leukaemia virus.
Morphological transformation of rat embryo cells by the combined action of 3-methylcholanthrene and Rauscher leukaemia virus.
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3-甲基胆蒽和Rauscher白血病病毒联合作用对大鼠胚胎细胞的形态转化。
DOI：
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发表时间：
1971
期刊：
影响因子：
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通讯作者：
Robert J. Huebner
中科院分区：
文献类型：
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作者：
Paul J. Price;Aaron E. Freeman;William T. Lane;Robert J. Huebner
感染CF-1或Rauscher c型RNA小鼠白血病病毒的大鼠胚胎细胞，在用二乙基亚硝胺（DENA）处理后，发生形态转变，成为非整倍体1。未经处理的细胞和仅用病毒或化学物质处理的细胞都不会转化。我们在这里描述了3-甲基胆蒽（3mc）对感染劳舍尔白血病病毒的大鼠细胞的类似作用。
RAT embryo cells infected with either CF-1 or Rauscher C-type RNA murine leukaemia virus, when treated with diethylnitrosamine (DENA), undergo morphological transformation and become aneuploid1. Untreated cells and cells treated with either virus or chemical alone do not transform. We describe here a similar effect of 3-methylcholanthrene (3 MC) on rat cells infected with Rauscher leukaemia virus.