Cerebral aneurysm wall thickness analysis using intraoperative microscopy: effect of size and gender on thin translucent regions
Cerebral aneurysm wall thickness analysis using intraoperative microscopy: effect of size and gender on thin translucent regions
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DOI：
10.1136/neurintsurg-2012-010285
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发表时间：
2013-05-01
影响因子：
4.8
通讯作者：
Malek, Adel M.
中科院分区：
文献类型：
--
作者：
Kadasi, Laith M.;Dent, Walter C.;Malek, Adel M.
目的脑动脉瘤的壁厚是一个文献很少的特征，它可以为动脉瘤的适应性生长、动脉瘤破裂的风险和对血管内治疗的反应提供信息。通过术中视频显微镜观察动脉瘤壁厚度的分布。方法根据显微手术夹持术中影像资料，选择54例未破裂的脑囊性动脉瘤。在穹顶的超薄、半透明、中间和厚区，通过颜色半透明和像素值定量来评估动脉瘤的壁厚分布。我们分析了动脉瘤的形态、位置和相关的人口学因素。结果所有圆顶组织特征的平均比例为：超薄27%，中等65%，厚8%。有最大尺寸D-max的较小的动脉瘤
Objective Wall thickness is a poorly documented characteristic of cerebral aneurysms which may provide insight into adaptive aneurysmal growth, aneurysm rupture risk and response to endovascular treatment. The distribution of aneurysm wall thickness, as observed by intraoperative video microscopy, is described.Methods 54 unruptured saccular cerebral aneurysms were selected based on the availability of intraoperative video obtained from patients undergoing microsurgical clipping. Aneurysms were assessed for the distribution of wall thickness based on color translucence and quantitation of pixel values at superthin translucent, intermediate and thick regions of the dome. The data were analyzed with respect to aneurysm morphology, location and associated demographic factors.Results The mean proportions of tissue characteristic among all domes analyzed were found to be 27% superthin, 65% intermediate, and 8% thick. Smaller aneurysms having a maximal dimension D-max