Event-related potential features indexing central auditory discrimination by newborns
Event-related potential features indexing central auditory discrimination by newborns
复制标题
DOI：
10.1016/s0926-6410(01)00093-3
复制
发表时间：
2002-02-01
期刊：
影响因子：
--
通讯作者：
Näätänen, R
中科院分区：
文献类型：
--
作者：
Ceponiene, R;Kushnerenko, E;Näätänen, R
行为研究已经产生的证据很少的声音特征的歧视，在新生儿。听觉事件相关电位（ERPs）的负性失配（MMN）成分可以研究声音感知的感觉过程，它不依赖于有意识的感知和反应。因此，MMN适合于研究新生儿，谁是难以获得的行为反应。因此，本研究利用频谱丰富的声音，已知引起最可复制的MMN在成人中，调查新生儿的声音持续时间和频率变化的前注意分析。还试图控制强制性ERP对MMN的影响。本文对55例新生儿在时程和频率奇球条件下的三个部分谐波音进行了研究。在其他两个，等概率的持续时间和等概率的频率，条件频率和持续时间偏离的古怪范例之间的声音的其他持续时间和频率的概率相等。在频率奇球条件下，81%的新生儿和78%的新生儿在持续时间奇球条件下诱发MMN。持续时间条件下，MMN的时程和频率波幅无显著差异，但MMN潜伏期延长。强制性成分似乎对持续时间的偏离标准差异有显著贡献，但对频率条件无显著影响。大多数新生儿似乎具有有效的声音频率和持续时间的辨别机制。他们的前注意的声音歧视是促进频谱丰富的声音内容。目前的研究结果支持新生儿MMN的变化检测性质，但是，声音持续时间相关的强制性影响需要考虑到婴儿MMN的研究。(C)2002 Elsevier Science B.V.保留所有权利。
Behavioral research has produced little evidence on sound feature discrimination in neonates. Sensory processes underlying sound perception can be studied using the mismatch negativity (MMN) component of auditory event-related potentials (ERPs), which is not contingent on conscious perception and response. Thus, MMN is suitable for studying newborns, who are difficult to obtain behavioral responses from. The present study thus utilized spectrally rich sounds, known to elicit the most replicable MMN in adults, to investigate newborns' preattentive analysis of sound duration and frequency changes. An attempt was also made to control for the obligatory ERP effects on the MMN. Three-partial harmonic tones were presented in Duration and in Frequency oddball conditions to 55 newborns. In the other two, Equiprobable duration and Equiprobable frequency, conditions frequency and duration deviants of the oddball paradigms were presented with equal probabilities among sounds of other durations and frequencies. MMN was elicited in 81% of newborns in Frequency oddball condition and in 78% of newborns in Duration oddball condition. No significant amplitude differences between the duration and frequency MMNs were found, but MMN latency was delayed in Duration condition. The obligatory components seemed to contribute significantly to the deviant-standard difference in Duration but not in Frequency condition. The majority of neonates appear to possess effective sound frequency and duration discrimination mechanisms. Their preattentive sound discrimination is facilitated by spectrally rich sound content. The present findings support a change-detection nature of MMN in neonates; however, sound duration-related obligatory effects need to be taken into account in infant MMN studies. (C) 2002 Elsevier Science B.V. All rights reserved.