Intake of Own Mother's Milk during the First Days of Life Is Associated with Decreased Morbidity and Mortality in Very Low Birth Weight Infants during the First 60 Days of Life

Intake of Own Mother's Milk during the First Days of Life Is Associated with Decreased Morbidity and Mortality in Very Low Birth Weight Infants during the First 60 Days of Life
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DOI:
10.1159/000341335
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发表时间:
2012-01-01
期刊:
影响因子:
2.5
通讯作者:
Vermeulen, Marijn J.
Vermeulen, Marijn J.
中科院分区:
医学2区
文献类型:
--
作者:
Corpeleijn, Willemijn E.;Kouwenhoven, Stefanie M. P.;Vermeulen, Marijn J.

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背景:与配方奶喂养的婴儿相比,母乳喂养的早产儿坏死性小肠结肠炎(NEC)和脓毒症的发生率较低。目前尚不清楚这是由母乳的保护特性还是由于缺乏牛奶造成的。特别是在生命早期,早产儿往往无法获得母乳,而立即开始进行最低限度的肠内营养。目的:确定在生命最初几天摄入母乳与脓毒症、NEC和长期死亡的综合结局之间是否存在关联。方法:对出生体重不达标的婴儿进行回顾性研究
Background: The incidence of necrotizing enterocolitis (NEC) and possibly also of sepsis is lower in preterm infants fed their own mother's milk (hereafter 'mother's milk') compared with formula-fed infants. It is unclear whether this is caused by the protective properties of breast milk or by the absence of cow's milk. Especially in early life, mother's milk is often unavailable to preterm infants, while minimal enteral nutrition is initiated immediately. Objectives: To determine whether there is an association between intake of mother's milk during the first days of life and the combined outcome of sepsis, NEC and death over a prolonged period. Methods: Retrospective study in infants with a birth weight