The regulation of respiration and circulation during the initial stages of muscular work
The regulation of respiration and circulation during the initial stages of muscular work
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DOI：
10.1113/jphysiol.1913.sp001616
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发表时间：
1913-10
期刊：
影响因子：
--
通讯作者：
A. Krogh;J. Lindhard
中科院分区：
文献类型：
--
作者：
A. Krogh;J. Lindhard
本文拟描述人在轻或重工作的最初几分钟内发生的通气量、血流量、脉率、呼吸交换和肺泡CO2张力的变化，并试图进一步探讨这些变化的机理。本文用自行车测功仪和呼吸器进行了实验，并对所用技术的主要部分作了详细的阐述。我们在六种不同的植物上做了实验。三个这样的，F. N.还有J. J他们或多或少都受过突然用力的训练，而另外三个人虽然能长时间做相当多的工作，却没有受过突然用力的训练。当被告知要从一个重负荷开始时，前面提到的三个受试者会以非常快的速度开始开始，但很快就下降了，而其他三个受试者即使被告知要尽可能快地开始，也会相对缓慢地开始开始，并在一定的时间内逐渐恢复。（例如，Exp。第十和第九卷，第135页）关于杰杰，J. K.和H.我们只在不同条件下测定了肺容量、通气量和做功率。在A. K.和F. N.我们已经做了一些“完整的“实验，包括在几个时刻，特别是在工作的第一分钟，测定呼吸交换和肺泡空气的组成。对J. L.该受试者的呼吸深、慢且非常有规律，这极大地促进了肺泡空气的正确采样。我们希望明确地声明--尽管这似乎是多余的--在所有情况下的呼吸（除了当受试者被告知呼吸时
IN the present paper we propose to describe the changes in ventilation, blood flow, pulse rate, respiratory exchange and alveolar CO2 tension taking place in man during the first few minutes of light or heavy work and we shall attempt further an inquiry into the mechanism of these changes. The experinments have been made by means of the bicycle ergometer and respiration apparatus described in another paper' in which also the main parts of the technique employed have been set forth in detail. We have made experiments on six different suibjects. Three of these, J. L., F. N. and J. J., are trained, mnore or less, to sudden and violent exertions, while the other three, though able to do a fair amount of work over a long period, are not trained to sudden exertions. When told to start with a heavy load the three first named subjects will begin at a very rapid rate, which soon declines, while the other threeeven when told to start as rapidly as possible, and meaning to do sowill begin comparatively slowly and work up during a certain time. (Compare for example Exps. X and IX, p. 135.) On the subjects J. J., J. K. and H. P. we have made determinations of pulmonary volumes, ventilations and rates of work only, under varying conditions. On A. K. and F. N. we have made a few " complete " experiments involving determinations of the respiratory exchange and the composition of the alveolar air at several moments, especially during the first minute of work. The most detailed study has been made on J. L. The respiration of this subject is deep, slow and extremely regular, which greatly facilitates the correct sampling of the alveolar air. We wish to state explicitly-though it may seem superfluous-that the breathing in all cases (except when a subject was told to breathe