Dexamethasone suppression test in psychiatric patients with psychoactive substance dependence.

Dexamethasone suppression test in psychiatric patients with psychoactive substance dependence.
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精神活性物质依赖精神病患者的地塞米松抑制试验。

DOI:
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发表时间:
1991
期刊:
The American Journal of Drug and Alcohol Abuse
影响因子:
--
通讯作者:
J. Scibilia
J. Scibilia
中科院分区:
--
文献类型:
--
作者:
A. A. Olivera;D. Fero;J. Scibilia

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对374名同时存在物质依赖(包括酒精)的慢性精神病患者进行地塞米松抑制试验(DST)的研究发现,97%的非抑制与情感性障碍相关。非抑制性发生率在重度抑郁障碍中为38.5%,在双相情感障碍中为27.7%。该研究没有发现非抑制发生率与任何特定药物组之间的明显联系。情感性障碍患者的pre地塞米松血药浓度高于其他诊断。结论是,在药物滥用人群中,DST可能作为诊断重度抑郁症的临床方法的一部分具有价值。
The study of the dexamethasone suppression test (DST) in 374 chronic psychiatric patients with concurrent substance dependence, including alcohol, found 97% of nonsuppression associated with affective disorders. The incidence of nonsuppression was 38.5% in major depressive disorder and 27.7% in bipolar affective disorder. This study found no apparent connection between the incidence of nonsuppression and any particular drug group. Predexamethasone plasma concentrations were higher in affective disorders than in other diagnoses. It is concluded that the DST may be of value as part of the clinical approach to the diagnosis of major depressive disorders in a substance-abusing population.
地塞米松抑制试验在精神病学中有临床用途吗?
DOI: --
发表时间: 1985
期刊: The Journal of clinical psychiatry
影响因子: --
作者:
Baldessarini,RJ;Arana,GW
通讯作者: Arana,GW
酒精中毒患者的地塞米松抑制试验。
DOI: --
发表时间: 1983
影响因子: 10.6
作者:
Kroll,P;Palmer,C;Greden,JF
通讯作者: Greden,JF