Semiquantitative Gallium Scintigraphy in Patients with Osteogenic Sarcoma
Semiquantitative Gallium Scintigraphy in Patients with Osteogenic Sarcoma
复制标题
骨肉瘤患者的半定量镓闪烁扫描
DOI：
10.1097/00003072-198404000-00001
复制
发表时间：
1984
影响因子：
10.6
通讯作者：
R. Benua
中科院分区：
文献类型：
--
作者：
S. Yeh;G. Rosen;B. Caparros;R. Benua
对37例新诊断的骨肉瘤患者进行了顺序镓扫描。在10至19岁年龄组的男性和股骨病变中发现更多的高镓摄取。高摄取率也见于X线片上以成骨细胞或混合性改变为主的患者和软组织肿块患者。化疗后，对治疗有反应的患者肿瘤/非肿瘤比率显著降低，如整块切除时组织学检查的III或IV级反应所示。结论：半定量镓核素显像可用于监测骨肉瘤患者的治疗反应。
Sequential gallium scans were performed in 37 patients with newly diagnosed osteogenic sarcoma. High gallium uptake was found more often in males in the 10 to 19 age group and in femoral lesions. High uptake was also seen in patients who had predominantly osteoblastic or mixed changes on radiographs and in those who had a soft tissue mass. Following chemotherapy, significant decrease of tumor to nontumor ratio occurred in the patients who responded to treatment as shown by a Grade III or IV response on histologic examinations at the time of en bloc resection. It is concluded that semiquantitative gallium scintigraphy is useful in monitoring therapeutic response in patients with osteogenic sarcoma.