GUIDELINES FOR WORKING WITH RODENTS POTENTIALLY INFECTED WITH HANTAVIRUS

GUIDELINES FOR WORKING WITH RODENTS POTENTIALLY INFECTED WITH HANTAVIRUS
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DOI:
10.2307/1382742
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发表时间:
1995-08-01
影响因子:
1.7
通讯作者:
PETERS, CJ
PETERS, CJ
中科院分区:
生物学3区
文献类型:
--
作者:
MILLS, JN;YATES, TL;PETERS, CJ

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由于汉他病毒肺综合征的发病率和死亡率较高,以及汉他病毒气溶胶传播的可能性,在野外、实验室或教室中处理已知储库种的人员应采取特殊预防措施,以尽量减少感染风险。我们提供了具体的个人安全指南,而陷阱,处理和释放,运输,采样,并对潜在感染的啮齿动物进行尸检,或在水库物种占据的地区进行实地教学。应特别考虑呼吸保护、消毒剂的选择和使用、仪器和捕集器的去污、感染性废物的适当处置以及用于汉他病毒检测的样本的保存和运输。建议对用于启动实验室菌落的野生啮齿动物进行预防性测试。虽然我们专门针对汉坦病毒,但当涉及可通过气溶胶传播并能引起高发病率和死亡率的传染性人畜共患病因子时,所描述的程序适用于对小型哺乳动物种群的任何研究。
Because of the high morbidity and mortality associated with hantavirus pulmonary syndrome and the possibility of aerosol transmission of hantaviruses, persons handling known reservoir species in the field, laboratory, or classroom should take special precautions to minimize the risk of infection. We provide specific guidelines for personal safety while trapping, handling and releasing, transporting, sampling, and performing necropsy on potentially infected rodents or teaching field classes in areas occupied by reservoir species. Special consideration should be given to respiratory protection, choice and use of disinfectants, decontamination of instruments and traps, proper disposal of infectious wastes, and preservation and shipment of samples intended for hantavirus testing. Precautionary testing of wild rodents used to start laboratory colonies is recommended. Although we specifically address hantaviruses, the procedures described are applicable for any study of populations of small mammals when an infectious zoonotic agent transmissible by aerosol and capable of causing high morbidity and mortality is involved.