SERUM URIC-ACID IN ENGLAND AND SCOTLAND
SERUM URIC-ACID IN ENGLAND AND SCOTLAND
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DOI：
10.1136/ard.36.5.420
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发表时间：
1977-01-01
影响因子：
27.4
通讯作者：
BUCHANAN, WW
中科院分区：
文献类型：
--
作者：
STURGE, RA;SCOTT, JT;BUCHANAN, WW
对来自2个英格兰地区的512名男性和254名女性以及来自1个苏格兰地区的337名男性进行了血清尿酸（SUA）测定。男性的平均SUA水平相同（5.5 mg/100 ml），女性相似（3.9和4.1 mg/100 ml）。苏格兰人痛风的明显罕见性不能用SUA水平的地区差异或高尿酸血症（定义为SUA ≥ 7.0 mg/100 ml）患病率的地区差异来解释，高尿酸血症在英国男性和苏格兰男性中分别为6.6%和8%。SUA与体重、血清尿素呈正相关，女性与年龄呈正相关，但与社会阶层无关。体重是男性和女性SUA最重要的预测因子，并且上级于涉及身高校正的测量，如体重指数和计算的瘦体重。
Serum uric acid (SUA) was measured in 512 men and 254 women from 2 English regions and in 337 men from 1 Scottish region. Mean SUA levels were the same in the men (5.5 mg/100 ml) and similar in the women (3.9 and 4.1 mg/100 ml). The apparent rarity of gout in Scotsmen cannot be explained by regional differences in SUA levels or in the prevalence of hyperuricemia (defined as SUA of 7.0 mg/100 ml or over) which was present in 6.6% of the English men and 8% of the Scots. SUA was positively correlated with weight and serum urea, and with age in women, but no variation was found with social class. Body weight was the most important predictor of SUA in both men and women and superior to measurements involving correction for height, such as ponderal index and calculated lean body mass.