Design and implementation of a highly selective minimal self-replicating system
Design and implementation of a highly selective minimal self-replicating system
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DOI：
10.1002/anie.200601845
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发表时间：
2006-01-01
影响因子：
16.6
通讯作者：
Philp, Douglas
中科院分区：
文献类型：
--
作者：
Kassianidis, Eleftherios;Philp, Douglas
自我导向：合理设计的自我互补模板（见图）能够复制，从而从反应混合物中放大自身，排除其非对映体。这种方法允许高度选择性的放大，通过聚焦于显示与过渡状态高度互补的模板。(图)。
Self-direction: A rationally designed self-complementary template (see picture) is capable of replication, thereby amplifying itself from a reaction mixture to the exclusion of its diastereomer. This approach allows a highly selective amplification by focusing on templates that display a high level of complementarity to transition states.(Figure Presented).