PRODUCTION AND CHARACTERIZATION OF SLIME POLYSACCHARIDE OF PSEUDOMONAS-AERUGINOSA
PRODUCTION AND CHARACTERIZATION OF SLIME POLYSACCHARIDE OF PSEUDOMONAS-AERUGINOSA
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DOI：
10.1128/jb.116.2.915-924.1973
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发表时间：
1973-01-01
影响因子：
3.2
通讯作者：
LINKER, A
中科院分区：
文献类型：
--
作者：
EVANS, LR;LINKER, A
本文研究了从多种人体感染中分离的铜绿假单胞菌产生的粘液多糖。当存在足够量的碳水化合物时，在高渗透压或蛋白质供应不足的条件下，培养中的粘液生产似乎是最佳的。该菌产生的多糖与棕色固氮菌（Azotobacter vinelandii）的粘液和海藻藻酸相似。它们由β-1，4-linkedd-甘露糖醛酸残基和不同量的5-差向异构体-古洛糖醛酸组成。所有细菌聚合物都含有海藻酸盐中不存在的邻乙酰基。多糖的甘露糖醛酸与古洛糖醛酸含量的比率和o-乙酰基的数目有很大的不同。粘液的特殊组成没有被发现是疾病过程的特征，从该疾病过程中，P.获得了空气动力学方程。
The slime polysaccharides produced byPseudomonas aeruginosaisolated from a variety of human infections were investigated. Slime production in culture seemed optimal when adequate amounts of carbohydrate were present and under conditions of either high osmotic pressure or inadequate protein supply. The polysaccharides produced by the organisms were similar to each other, to the slime ofAzotobacter vinelandii, and to seaweed alginic acids. They were composed of β-1,4-linkedd-mannuronic acid residues and variable amounts of its 5-epimerl-guluronic acid. All bacterial polymers containedo-acetyl groups which are absent in the alginates. The polysaccharides differed considerably in the ratio of mannuronic to guluronic acid content and in the number ofo-acetyl groups. The particular composition of the slime was not found to be characteristic for the disease process from which the mucoid variants ofP. aeruginosawere obtained.