ArrayNinja: An Open Source Platform for Unified Planning and Analysis of Microarray Experiments.
ArrayNinja: An Open Source Platform for Unified Planning and Analysis of Microarray Experiments.
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DOI：
10.1016/bs.mie.2016.02.002
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发表时间：
2016
影响因子：
--
通讯作者：
Rothbart SB
中科院分区：
文献类型：
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作者：
Dickson BM;Cornett EM;Ramjan Z;Rothbart SB
基于微阵列的蛋白质组平台已经成为研究蛋白质功能的各个方面的有价值的工具，特别是在染色质生物化学领域。微阵列技术本身在可打印材料和平台设计方面基本上是不受限制的，高效的多维分析参数优化需要在定制打印布局的设计和分析中具有流动性。这促使了对简化的软件基础设施的需求，以促进定制微阵列实验的组合规划和分析。为此，我们开发了ArrayNimpa，作为一种便携式、开源和交互式应用程序，它统一了微阵列实验的计划和可视化，并为最终用户提供了最大的灵活性。可以计划阵列实验，将其存储到专用数据库中，并将其与成像结果合并，以实现目前利用现有的微阵列信息学工具无法实现的数据交互和集中程度。
Microarray-based proteomic platforms have emerged as valuable tools for studying various aspects of protein function, particularly in the field of chromatin biochemistry. Microarray technology itself is largely unrestricted in regard to printable material and platform design, and efficient multidimensional optimization of assay parameters requires fluidity in the design and analysis of custom print layouts. This motivates the need for streamlined software infrastructure that facilitates the combined planning and analysis of custom microarray experiments. To this end, we have developed ArrayNinja as a portable, open source, and interactive application that unifies the planning and visualization of microarray experiments and provides maximum flexibility to end users. Array experiments can be planned, stored to a private database, and merged with the imaged results for a level of data interaction and centralization that is not currently attainable with available microarray informatics tools.