An Audit of the Quality of Reporting and Bias of Studies on Yoga in Epilepsy
An Audit of the Quality of Reporting and Bias of Studies on Yoga in Epilepsy
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DOI：
10.4103/0028-3886.359244
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发表时间：
2022-09-01
期刊：
影响因子：
2.7
通讯作者：
Xaviar, Suja
中科院分区：
文献类型：
--
作者：
Das, Saibal;Tiwari, Sayali;Xaviar, Suja
背景：瑜伽越来越多地被用作药物治疗癫痫的补充治疗模式；然而，关于瑜伽治疗癫痫的研究的报道质量和偏倚尚不确定。目的：系统评价已发表的关于瑜伽治疗癫痫的研究的报道质量和偏倚。材料和方法：检索PubMed和Cochrane数据库，研究瑜伽治疗癫痫的疗效，或描述患者或护理人员对瑜伽治疗癫痫的知识、态度、影响和实践。采用标准报告清单（CONSORT、STROBE、COREQ和修改后的CONSORT）评价研究的报告质量，并根据研究设计采用标准工具（Cochrane协作的偏倚风险工具、Newcastle-Ottawa量表和ROBINS-I工具）评估偏倚风险。结果：纳入了15项研究（4项随机对照试验、7项观察性研究、3项非随机介入研究和1项混合方法研究）。从方法学角度来看，评估瑜伽对癫痫作用的研究报告质量相对较差，偏倚风险相对较高，而描述瑜伽对癫痫的认识、态度、影响和实践的研究报告偏倚风险相对较高。结论：瑜伽与癫痫相关研究的报道质量不令人满意，偏倚风险较高。因此，在广泛推荐瑜伽治疗癫痫之前，必须谨慎。
Background: Yoga is increasingly being used as a complementary mode of treatment for epilepsy along with pharmacotherapy; however, the quality of reporting and bias of studies on yoga in epilepsy is uncertain.Objective: This study was performed to systematically evaluate the reporting quality and bias of the published studies on yoga in epilepsy.Materials and methods: PubMed and Cochrane databases were searched for studies investigating the efficacy of yoga in epilepsy or describing the patients' or caregivers' knowledge, attitude, influence, and practice of yoga in epilepsy. The reporting qualities of the studies were appraised by standard reporting checklists (CONSORT, STROBE, COREQ, and modified CONSORT) and the risks of bias were assessed using standard tools (Cochrane Collaboration's risk of bias tool, Newcastle-Ottawa scale, and ROBINS-I tool) according to the study designs.Results: Fifteen studies (four randomized control trials, seven observational studies, three non-randomized interventional studies, and one was a mixed-method study) were included. The reporting qualities of the studies which evaluated the role of yoga in epilepsy were comparatively poor from the methodological perspective and the risks of bias were comparatively high than those which described the knowledge, attitude, influence, and practice of yoga in epilepsy.Conclusion: The reporting qualities of studies in relation to yoga and epilepsy were not satisfactory and the risks of bias were high. Hence, it is imperative to be cautious before widely recommending yoga in epilepsy.