Intranasal instillation of miR-410 targeting IL-4/IL-13 attenuates airway inflammation in OVA-induced asthmatic mice
Intranasal instillation of miR-410 targeting IL-4/IL-13 attenuates airway inflammation in OVA-induced asthmatic mice
复制标题
鼻内滴注 miR-410 靶向 IL-4/IL-13 可减轻 OVA- 诱导的哮喘小鼠的气道炎症
DOI:
10.3892/mmr.2018.9703
复制
发表时间:
2019-02-01
影响因子:
3.4
通讯作者:
Lin, Rongjun
中科院分区:
文献类型:
--
作者:
Jin, Rong;Hu, Sujuan;Lin, Rongjun
Asthma is a common chronic inflammatory respiratory disease characterised by airway inflammation and hyperresponsiveness. The present study was designed to clarify the effect of intranasal miR-410 administration in an ovalbumin (OVA)-induced murine model of asthma. It was found that miR-410 expression was significantly decreased in the lungs of OVA-induced asthmatic mice (P