Risk Factors in Early Implant Failure: A Meta-Analysis
Risk Factors in Early Implant Failure: A Meta-Analysis
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DOI：
10.1097/id.0000000000000386
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发表时间：
2016-04-01
影响因子：
--
通讯作者：
Testori, Tiziano
中科院分区：
文献类型：
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作者：
Manzano, Guillermo;Montero, Javier;Testori, Tiziano
背景：临床医生应该能够权衡与早期种植体失败相关的主要风险因素的作用。目的：该荟萃分析的目的是评估不同患者相关和植入物相关风险因素对早期植入物失效发生率的影响。材料和方法：2014年7月，检索了主要电子数据库中报告早期失败的研究。相关论文由2名独立作者使用预定义的选择标准选择。三位作者对纳入的研究进行独立评分，以进行质量评估。对所选文献中主要危险因素的估计比值比进行荟萃分析。结果：共纳入9项研究。共对18，171个种植体进行了荟萃分析，其中10，921个种植体进行了吸烟分析，15，260个种植体直径分析，16，075个种植体长度分析，16，711个种植体位置分析（上颌骨vs下颌骨）。早期种植体失败的主要显著风险因素是吸烟习惯（比值比[OR]，1.7; 95%置信区间[CI]，1.3，2.3）、种植体短于10 mm（OR，1.6; 95% CI，1.2，2.2）和种植体置于上颌骨（OR，1.3; 95% CI，1.0，1.6）。结论：临床医生应该意识到，在吸烟者、长度缩短的种植体和种植体支持的上颌骨康复的情况下，早期失败的风险会增加。
Background: Clinicians should be able to weigh the role of the main risk factors associated with early implant failure. Purpose: The aim of this meta-analysis was to assess the influence of different patient-related and implant-related risk factors on the occurrence of early implant failure. Materials and Methods: In July, 2014 the main electronic databases were searched for studies reporting on early failures. Relevant papers were selected by 2 independent authors using predefined selection criteria. Three authors independently scored the included studies for quality assessment. The estimated odds ratios of the main risk factors from the selected papers were subjected to meta-analysis. Results: Nine studies were included. A total of 18,171 implants were meta-analyzed, of which 10,921 were analyzed for smoking, 15,260 for implant diameter, 16,075 for implant length, and 16,711 for implant location (maxilla vs mandible). The main significant risk factors for early implant failures were the smoking habit (odds ratio [OR], 1.7; 95% confidence interval [CI], 1.3, 2.3), implants shorter than 10 mm (OR, 1.6; 95% CI, 1.2, 2.2) and implants placed in the maxilla (OR, 1.3; 95% CI, 1.0, 1.6). Conclusions: Clinicians should be aware of the increased risk of early failure in the presence of smokers, implants with reduced length, and implant-supported maxillary rehabilitation.