A posteriori respiratory gating in contrast ultrasound for assessment of hepatic perfusion
A posteriori respiratory gating in contrast ultrasound for assessment of hepatic perfusion
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DOI：
10.1088/0031-9155/50/19/003
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发表时间：
2005-10
影响因子：
3.5
通讯作者：
G. Renault;F. Tranquart;V. Perlbarg;A. Bleuzen;A. Herment;F. Frouin
中科院分区：
文献类型：
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作者：
G. Renault;F. Tranquart;V. Perlbarg;A. Bleuzen;A. Herment;F. Frouin
提出了一种新颖的策略，以尽量减少呼吸运动对肝脏超声造影研究的影响。它是基于动态图像序列的后验触发。它在以高时间分辨率（8图像s-1）采集的灌注研究中进行了测试，以实现参数成像。首先通过独立成分分析估计呼吸成分。该曲线的局部最小值和最大值的估计使我们能够选择两个帧子集，对应于吸气末平面和呼气末平面。这两个子集同时进行了分析，使用因子分析的医学图像序列。该方法确定了主要的造影剂摄取动力学及其相关的定位。首先在模拟研究中验证了全局策略，然后将其应用于11例患者的研究。在这两种情况下，帧选择被判断为相关的，并且是应用参数成像方法之前的必要的初步步骤。总之，提出的后验门控方法是肝脏超声造影研究局部量化的第一步。
An original strategy is proposed to minimize the impact of respiratory motion on hepatic contrast-enhanced ultrasound studies. It is based on the a posteriori triggering of dynamic image sequences. It was tested on perfusion studies acquired with a high temporal resolution (8 images s−1) to enable parametric imaging. A respiratory component was first estimated by independent component analysis. The estimation of the local minima and maxima of this curve enabled us to select two subsets of frames, corresponding to the end-of-inspiration plane and to the end-of-expiration plane. Both subsets were simultaneously analysed using factor analysis of medical image sequences. This method identified the main contrast uptake kinetics and their associated localizations. The global strategy was validated firstly on a simulated study and then applied to 11 patients' studies. In both cases, the frame selection was judged relevant and a necessary preliminary step before applying methods of parametric imaging. In conclusion, the a posteriori gating method that is proposed is a first step towards local quantification of hepatic contrast-enhanced ultrasound studies.