En face swept-source optical coherence tomography detecting thinning of inner retinal layers as an indicator of capillary nonperfusion
En face swept-source optical coherence tomography detecting thinning of inner retinal layers as an indicator of capillary nonperfusion
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DOI：
10.5301/ejo.5000514
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发表时间：
2015-03-01
影响因子：
1.7
通讯作者：
Murata, Toshinori
中科院分区：
文献类型：
--
作者：
Imai, Akira;Toriyama, Yuichi;Murata, Toshinori
目的：报道En Face扫描源光学相干断层扫描(SS-OCT)作为一种无创检测视网膜层变薄区域的方法，这些区域是视网膜分支静脉阻塞(BRVO)患者视网膜无灌注区(NPA)的潜在指标。我们计算了推测的NPA与相应的荧光素血管造影(FA)图像中确定的NPA之间的重叠对应比。结果：经FA测量的神经节细胞大小与推测的神经节细胞复合体大小具有较强的相关性(r=0.746，P<0.05)。
Purpose: To report en face swept-source optical coherence tomography (SS-OCT) as a noninvasive detection modality for regions of retinal layer thinning that are potential indicators of retinal nonperfusion areas (NPAs) in patients with branch retinal vein occlusion (BRVO).Methods: Thirty-one eyes of 46 patients with BRVO showing a definite retinal NPA larger than 1 disc in diameter within the vascular arcades were included in this study. We calculated the overlapping correspondence ratio between presumed NPA, which appeared as a dark area in en face SS-OCT, and definite NPA in corresponding fluorescein angiography (FA) images. The correlation between brightness in en face SS-OCT images and corresponding ganglion cell complex (GCC) thickness determined by SD-OCT GCC maps was evaluated as well.Results: Measured NPA size in FA and presumed NPA size in en face SS-OCT showed strong correlation (r = 0.746, p