Marrow or peripheral blood for hematopoietic engraftment.
Marrow or peripheral blood for hematopoietic engraftment.
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用于造血移植的骨髓或外周血。
DOI：
10.1056/nejm197707072970116
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发表时间：
1977
期刊：
影响因子：
--
通讯作者：
S. Perry
中科院分区：
文献类型：
--
作者：
R. Barr;J. Whang;S. Perry
致编辑：Storb等1认为正常人外周血可用作造血移植的补充细胞来源，这暗示着真正的造血干细胞会循环。这是一个我们同意的观点，2，它得到了来自临床经验的间接证据的支持。3 4 5在这方面，应该注意到，在人血液中可证实存在的祖细胞致力于沿着沿着建立的途径分化6 7 8 9 10与成功植入的目标无关，因为这些细胞具有有限的自我复制能力。11使用。
To the Editor: Implicit in the suggestion of Storb et al. 1 that normal human peripheral blood may be used as a supplementary source of cells for hematopoietic engraftment is the belief that true hematopoietic stem cells circulate. This is a view with which we concur, 2 and it has the support of circumstantial evidence derived from clinical experience. 3 4 5 In this regard it should be noted that the demonstrable presence, in human blood, of progenitor cells committed to differentiation along established pathways6 7 8 9 10 is irrelevant to the goal of successful engraftment, since these cells have a limited capacity for self-replication. 11 Using an.