Development, set-up and first results for a one-channel near-infrared spectroscopy system
Development, set-up and first results for a one-channel near-infrared spectroscopy system
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DOI：
10.1515/bmt.2008.005
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发表时间：
2008-01-01
期刊：
影响因子：
--
通讯作者：
Pfurtscheller, Gert
中科院分区：
文献类型：
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作者：
Bauernfeind, Guenther;Leeb, Robert;Pfurtscheller, Gert
近红外光谱（NIRS）是一种非侵入性光学技术，可用于评估人类大脑的功能活动。这项工作描述了一个设计用于光学脑机接口（BCI）的单通道NIRS系统的设置，并报告了在心算任务中脱氧血红蛋白（Hb）和氧合血红蛋白（HbO(2)）变化的首次测量。我们在13名健康受试者中发现了相对稳定和可重复的血流动力学反应。出乎意料的是，在前额叶皮层测量到的HbO(2)下降和Hb浓度增加，与之前报道的皮质激活期间典型的血流动力学反应（HbO(2)增加，Hb下降）形成对比。
Near-infrared spectroscopy (NIRS) is a non-invasive optical technique that can be used to assess functional activity in the human brain. This work describes the set-up of a one-channel NIRS system designed for use as an optical brain-computer interface (BCI) and reports on first measurements of deoxyhemoglobin (Hb) and oxyhemoglobin (HbO(2)) changes during mental arithmetic tasks. We found relatively stable and reproducible hemodynamic responses in a group of 13 healthy subjects. Unexpected observations of a decrease in HbO(2) and increase in Hb concentrations measured over the prefrontal cortex were in contrast to the typical hemodynamic responses (increase in HbO(2) decrease in Hb) during cortical activation previously reported.