Fiber type composition of the vastus lateralis muscle of young men and women
Fiber type composition of the vastus lateralis muscle of young men and women
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DOI：
10.1177/002215540004800506
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发表时间：
2000-05-01
影响因子：
3.2
通讯作者：
Toma, K
中科院分区：
文献类型：
--
作者：
Staron, RS;Hagerman, FC;Toma, K
这项研究提出了在过去10年中收集的数据对肌肉纤维类型组成的股外侧肌的年轻男性和女性。从自愿参加各种研究项目的55名女性（21.2 +/- 2.2岁）和95名男性（21.5 +/- 2.4岁）的股外侧肌进行活检。使用mATP酶组织化学将六种纤维类型（I，IC，IIC，IIA，IIAB和IIB）分类，并测量主要纤维类型（I，IIA和IIB）的横截面积。肌球蛋白重链（MHC）的含量进行了测定，从男性的所有样本和26个样本的女性。除IC型肌纤维外，男女间肌纤维类型分布无显著差异。男性和女性的股外侧肌均含有约41%的I、1%的IC、1%的IIC、31%的IIA、6%的IIAB和20%的IIB。然而，所有三种主要纤维类型的横截面积男性比女性大。此外，男性的IIA型纤维最大，而女性的IIA型纤维往往最大。因此，每种特定纤维类型所占面积存在性别差异：男性IIA>I>IIB，女性I>IIA>IIB。这些数据建立了未受过训练的年轻男性和女性的基于mATP酶的纤维类型分布和尺寸的标准值。
This study presents data collected over the past 10 years on the muscle fiber type composition of the vastus lateralis muscle of young men and women. Biopsies were taken from the vastus lateralis muscle of 55 women (21.2 +/- 2.2 yr) and 95 men (21.5 +/- 2.4 yr) who had volunteered to participate in various research projects. Six fiber types (I, IC, IIC, IIA, IIAB, and IIB) were classified using mATPase histochemistry, and cross-sectional area was measured for the major fiber types (I, IIA, and IIB). Myosin heavy chain (MHC) content was determined electrophoretically on all of the samples from the men and on 26 samples from the women. With the exception of fiber Type IC, no significant differences were found between men and women for muscle fiber type distribution. The vastus lateralis muscle of both the men and women contained approximately 41% I, 1% IC 1% IIC, 31% IIA, 6% IIAB, and 20% IIB. However, the cross-sectional area of all three major fiber types was larger for the men compared to the women. In addition, the Type IIA fibers were the largest for the men, whereas the Type fibers tended to be the largest for the women. Therefore, gender differences were found with regard to the area occupied by each specific fiber type: IIA>I>IIB for the men and I>IIA>IIB for the women. These data establish normative values for the mATPase-based fiber type distribution and sizes in untrained young men and women.