STRUCTURAL AND FUNCTIONAL-ASPECTS OF PORCINE PLACENTAL MICROVASCULATURE
STRUCTURAL AND FUNCTIONAL-ASPECTS OF PORCINE PLACENTAL MICROVASCULATURE
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DOI：
10.1007/bf00304738
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发表时间：
1988-01-01
期刊：
影响因子：
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通讯作者：
DANTZER, V
中科院分区：
文献类型：
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作者：
LEISER, R;DANTZER, V
猪胎盘的微血管结构进行了研究，通过一系列半薄组织切片的光学显微镜，这是比较与扫描电子显微镜的人工暴露的母胎接触面，以及从母亲，胎儿，并结合母亲和胎儿侧制备的血管铸型。从暴露的表面以及猫的表面浮雕几乎与互补的母体和胎儿侧相同。为了满足快速生长的胎儿进行母胎交换的生理需要，这些浮雕在妊娠期间从简单系统发展到更复杂的系统，并且可以描述如下：（1）胎儿脊或球状突起与不同顺序的母体脊之间的联锁程度增加，这些胎儿脊或球状突起与不同深度的母体槽分开，在血管铸型上最清楚地看到。它创造了一个三维的缺口安排，加强了母胎接触区。(2)前毛细血管的结构以及网状结构，以及母体和胎儿侧的毛细血管的直径，在妊娠期间适应，使含氧血良好地分布到母体毛细血管中;这些，随着胎儿侧大的预防性连接毛细血管的发育，有利于胎儿血氧压的高动静脉差。(3)子宫内膜的血管结构和胎儿的脊和槽发展成一个逆流到逆流的母胎血液相互关系。因此，我们对猪胎盘中母胎毛细血管相互关系的证明表明，后者是一个比迄今所认为的更有效的交换器官。
The microvascular architecture of the pig placenta was studied by serial semithin histological sections for light microscopy, which were compared with scanning electron microscopy of artificially exposed materno-fetal contact surfaces as well as of vessel casts prepared from the maternal, fetal, and combined maternal and fetal sides. The superficial reliefs from the exposed surfaces as well as from the cats are almost identical with the complementary maternal and fetal sides. In order to meet the physiological needs of materno-fetal exchange for the rapidly growing fetuses, these reliefs develop from a simple to a more complex system during pregnancy and can be described as follows: (1) The degree of interlocking increases between the fetal ridges or bulbous protrusions and maternal ridges of different orders separated by maternal troughs of variable depth, most clearly seen on vessel casts. It creates a three-dimensional notch-arrangement, giving strength to the materno-fetal contact area. (2) The structure of precapillary vessels as well as of the meshwork, and the diameter of capillaries of the maternal and fetal sides, adapt during gestation giving a good distribution of oxygenated blood into the maternal capillaries; these, with the development of large prevenous connecting capillaries on the fetal side, favour a high arterio-venous difference of fetal blood O2 pressure. (3) The vascular architecture of endometrial and fetal ridges and troughs develop into a crosscurrent to countercurrent materno-fetal blood interrelationship. Our demonstration of the materno-fetal capillary interrelationship in the porcine placenta thus shows that the latter is a much more efficient organ for exchange than hitherto assumed.