Decoding the visual and subjective contents of the human brain
Decoding the visual and subjective contents of the human brain
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DOI：
10.1038/nn1444
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发表时间：
2005-05-01
影响因子：
25
通讯作者：
Tong, F
中科院分区：
文献类型：
--
作者：
Kamitani, Y;Tong, F
人类神经成像读出一个人精神状态的详细内容的潜力还没有得到充分的探索。我们研究了是否可以从功能磁共振成像(FMRI)测量的人脑活动中破译边缘方向的感知，这是一种基本的视觉特征。使用统计算法对大脑状态进行分类，我们发现早期视觉区域的整体fMRI信号可以可靠地在个体试验中预测受试者看到的八个刺激方向中的哪一个。此外，当受试者必须注意到两个重叠的正交栅中的一个时，基于特征的注意强烈地偏向于所关注的方向的总体活动。这些结果表明，包括初级视觉皮质(V1)在内的早期视觉区域的fMRI活动模式包含详细的方位信息，可以可靠地预测主观知觉。我们的方法为读出人脑中微调的表示及其主观内容提供了一个框架。
The potential for human neuroimaging to read out the detailed contents of a person's mental state has yet to be fully explored. We investigated whether the perception of edge orientation, a fundamental visual feature, can be decoded from human brain activity measured with functional magnetic resonance imaging (fMRI). Using statistical algorithms to classify brain states, we found that ensemble fMRI signals in early visual areas could reliably predict on individual trials which of eight stimulus orientations the subject was seeing. Moreover, when subjects had to attend to one of two overlapping orthogonal gratings, feature-based attention strongly biased ensemble activity toward the attended orientation. These results demonstrate that fMRI activity patterns in early visual areas, including primary visual cortex (V1), contain detailed orientation information that can reliably predict subjective perception. Our approach provides a framework for the readout of fine-tuned representations in the human brain and their subjective contents.