Trichocadinins B-G: Antimicrobial Cadinane Sesquiterpenes from Trichoderma virens QA-8, an Endophytic Fungus Obtained from the Medicinal Plant Artemisia argyi
Trichocadinins B-G: Antimicrobial Cadinane Sesquiterpenes from Trichoderma virens QA-8, an Endophytic Fungus Obtained from the Medicinal Plant Artemisia argyi
复制标题
Trichocadinins B-G：来自木霉 QA-8 的抗菌卡丁烷倍半萜烯，木霉是一种从药用植物艾叶中获得的内生真菌
DOI：
10.1021/acs.jnatprod.9b00139
复制
发表时间：
2019-09-01
影响因子：
5.1
通讯作者：
Wang, Bin-Gui
中科院分区：
文献类型：
--
作者：
Shi, Xiao-Shan;Meng, Ling-Hong;Wang, Bin-Gui
天花粉蛋白B-G(1-6)是从药用植物艾蒿(Artemisia Argyi)新鲜内生真菌--绿色木霉(Trichoderma virens QA-8)的培养提取液中分离得到的6个新的具有C-14羧基功能的木聚糖型倍半萜衍生物。通过对核磁共振波谱和质谱学数据的解释，确定了它们的结构。化合物1和3的结构和绝对构型经X-射线单晶分析得到确证。化合物1-3具有抗菌和抗真菌活性。
Trichocadinins B-G (1-6), six new cadinanetype sesquiterpene derivatives, each with C-14 carboxyl functionality, were isolated from the culture extract of Trichoderma virens QA-8, an endophytic fungus obtained from the fresh inner tissue of the medicinal plant Artemisia argyi. Their structures were elucidated by interpretation of the NMR spectroscopic and mass spectrometric data. The structures and absolute configurations of compounds 1 and 3 were confirmed by X-ray crystallographic analysis. Compounds 1-3 showed antibacterial and antifungal activity.