MECHANISM OF GROWTH AND RUPTURE IN CEREBRAL BERRY ANEURYSMS

MECHANISM OF GROWTH AND RUPTURE IN CEREBRAL BERRY ANEURYSMS
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DOI:
10.1136/bmj.1.5496.1138
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发表时间:
1966-01-01
影响因子:
--
通讯作者:
CROMPTON, MR
CROMPTON, MR
中科院分区:
医学1区
文献类型:
--
作者:
CROMPTON, MR

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一项研究开始评估手术缓解肺气肿引起的”不可逆”气道阻塞的可能性。52例患者进行了研究,临床和放射学检查,以及一般和区域肺功能检查。24例患者接受手术切除或折叠大疱或局部透辐射区。9例患者表现出明显的功能改善的证据。主观的改善与简单的解释性测试密切相关,尽管个别病例在其他参数上显示出更多的改善。一个值得注意的发现是6例基底病变患者中有5例的改善。选择病人的问题,手术的类型,和功能结果的意义进行了讨论。我们要感谢医学研究理事会的回旋加速器单位在哈默史密斯医院的成员,他们的专家帮助与'33“扫描。约翰·韦斯特博士在系列研究的早期对病人进行了检查,我们非常感谢他的帮助和建议。E小姐道格拉斯和护士N。Lamb在肺功能检查和支气管镜检查过程中提供了宝贵的帮助,而Len Smith先生和John霍尔顿先生则负责维护复杂的设备,包括质谱仪,该仪器在任何支气管镜检查过程中都没有出现故障。我们非常感谢来自不同医院的内科医生和外科医生,他们将患者转诊到我们这里进行评估,特别是那些在布朗普顿医院、圣乔治医院、米德赫斯特疗养院、圣赫勒医院和米尔福德胸科诊所的医生和外科医生。我们非常感谢我们的外科同事AM麦克阿瑟先生,感谢他在最近对该系列中大多数患者进行手术时的兴趣和合作。
An investigation was begun to assess thepossible surgical alleviation of" irreversible" airways obstruction due to emphysema. Fifty-two patients were studied by clinical and radiological examination, together with general and regional lung-function tests. Twenty-four patients were submitted to operation for resection or plication of bullae or localized trans-radiant areas. Nine patients showed clear evidence of func-tional improvement. Subjective improvement correlated most closely with the simple ventilatory tests, though isolated cases showed nmore improvement in other parameters. A notable finding was the improvement in five out of six patients who had basal lesions. The problems of selection of patients, the type of operation, and the significance of the functional results are discussed.We wish to thank members of the Medical Research Council's Cyclotron Unit at Hammersmith Hospital for their expert help with the'33Xe scans. Dr. John West was concerned with the examination of patients early in the series; we are most grateful for his help and advice. Miss E. Douglas and Nurse N. Lamb gave invaluable assistance with lung-function tests and the bronchoscopic procedures, while Mr. Len Smith and Mr. John Holden were responsible for maintaining the complex equipment, including the mass spectrometer, which did not fail during any bronchoscopic procedure. We are grateful to the physicians and surgeons from different hospitals who referred patients under their care to us for assessment, especially those at the Brompton Hospital, St. George's Hospital, Midhurst Sanatorium, St. Helier Hospital, and the Milford Chest Clinic. We are indebted to our surgical colleague, Mr. AM Macarthur, for his interest and cooperation in performing the surgery on most of the patients more recently in the series.