ProMod and Swiss-model: Internet-based tools for automated comparative protein modelling

ProMod and Swiss-model: Internet-based tools for automated comparative protein modelling
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DOI:
10.1042/bst0240274
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发表时间:
1996-02-01
影响因子:
3.9
通讯作者:
Peitsch, MC
Peitsch, MC
中科院分区:
生物学3区
文献类型:
--
作者:
Peitsch, MC

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在计划旨在理解蛋白质功能的实验时以及在药物设计过程中,对蛋白质三维结构的了解具有很大的帮助。然而,蛋白质三维结构的实验阐明常常受到难以获得足够的蛋白质和衍射晶体的阻碍,
Insights into the three-dimensional structure of a protein are of great assistance when planning experiments aimed at the understanding of protein function and during the drug design process. The experimental elucidation of the three-dimensional structure of proteins is, however, often hampered by difficulties in obtaining sufficient protein and diffracting crystals and