Multi-scale modelling of elastic moduli of trabecular bone
Multi-scale modelling of elastic moduli of trabecular bone
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DOI：
10.1098/rsif.2011.0814
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发表时间：
2012-07-07
影响因子：
3.9
通讯作者：
Liszka, Tadeusz
中科院分区：
文献类型：
--
作者：
Hamed, Elham;Jasiuk, Iwona;Liszka, Tadeusz
我们将松质骨模拟为具有分层结构的纳米复合材料，并预测其在不同结构尺度下的弹性性质。分析涉及自下而上的多尺度方法，从纳米尺度(矿化的胶原纤维)开始，向上延伸到亚微尺度(单层)、微尺度(单骨小梁)和中尺度(骨小梁)水平。分析中使用了连续介质细观力学方法、复合材料层合理论和有限元方法。理论结果与实验结果吻合较好。
We model trabecular bone as a nanocomposite material with hierarchical structure and predict its elastic properties at different structural scales. The analysis involves a bottom-up multi-scale approach, starting with nanoscale (mineralized collagen fibril) and moving up the scales to sub-microscale (single lamella), microscale (single trabecula) and mesoscale (trabecular bone) levels. Continuum micromechanics methods, composite materials laminate theory and finite-element methods are used in the analysis. Good agreement is found between theoretical and experimental results.