Does visual flicker phase at gamma frequency modulate neural signal propagation and stimulus selection?
Does visual flicker phase at gamma frequency modulate neural signal propagation and stimulus selection?
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DOI：
10.1167/12.4.5
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发表时间：
2012-01-01
影响因子：
1.8
通讯作者：
Driver, Jon
中科院分区：
文献类型：
--
作者：
Bauer, Markus;Akam, Thomas;Driver, Jon
神经元群体的振荡同步被认为在知觉整合和注意加工中发挥作用。然而，已经发现了一些相互矛盾的证据，其因果关系的感觉处理，特别是当使用闪烁的视觉刺激的目的是驱动振荡。我们测试psychopathically是否刺激之间的伽马频率闪烁（60 Hz）的相对相位调制公知的促进横向共线的Gabor补丁（实验1）或拥挤的外围目标之间的相互作用无关的干扰（实验2）。实验1评估了阈上Gabor侧翼对检测近阈值中央Gabor目标的影响（“横向相互作用范例”）。侧翼刺激可以彼此同相或反相闪烁。典型的促进目标检测发现与共线的侧翼，但这是不受闪烁相。实验2采用了“拥挤”的范例，其中周边目标伽柏补丁的方向歧视被破坏时，周围不相关的干扰。我们发现了通常的拥挤效应，随着空间分离而下降，但这不受目标和干扰物之间的相对闪烁相位的影响。这些结果意味着外部驱动的伽马频率相位的操纵不能调制视觉中的感知整合。
Oscillatory synchronization of neuronal populations has been proposed to play a role in perceptual integration and attentional processing. However, some conflicting evidence has been found with respect to its causal relevance for sensory processing, particularly when using flickering visual stimuli with the aim of driving oscillations. We tested psychophysically whether the relative phase of gamma frequency flicker (60 Hz) between stimuli modulates well-known facilitatory lateral interactions between collinear Gabor patches (Experiment 1) or crowding of a peripheral target by irrelevant distractors (Experiment 2). Experiment 1 assessed the impact of suprathreshold Gabor flankers on detection of a near-threshold central Gabor target ("Lateral interactions paradigm"). The flanking stimuli could flicker either in phase or in anti-phase with each other. The typical facilitation of target detection was found with collinear flankers, but this was unaffected by flicker phase. Experiment 2 employed a "crowding" paradigm, where orientation discrimination of a peripheral target Gabor patch is disrupted when surrounded by irrelevant distractors. We found the usual crowding effect, which declined with spatial separation, but this was unaffected by relative flicker phase between target and distractors at all separations. These results imply that externally driven manipulations of gamma frequency phase cannot modulate perceptual integration in vision.