Recent advances in recognition elements of food and environmental biosensors: A review
Recent advances in recognition elements of food and environmental biosensors: A review
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DOI：
10.1016/j.bios.2010.07.033
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发表时间：
2010-12-15
影响因子：
12.6
通讯作者：
Robbens, Johan
中科院分区：
文献类型：
--
作者：
Van Dorst, Bieke;Mehta, Jaytry;Robbens, Johan
对食品和环境中的污染物（如化合物、毒素和病原体）进行敏感监测，对于评估和避免对人类和环境健康的风险至关重要。为了实现这一点，非常需要灵敏、稳健和具有成本效益的生物传感器，使真实的时间和原位监测成为可能。由于其高灵敏度，选择性和通用性，亲和生物传感器是有趣的监测食品和环境中的污染物。抗体长期以来一直是最流行的基于亲和力的识别元件，然而最近大量的研究工作已经致力于开发具有改进的特性（如特异性、稳定性和成本效益）的新型识别元件。本文讨论了这些创新的亲和识别元件，即，双链，核酸和分子印迹聚合物，并给出了食品和环境中应用这些新的亲和识别元件的生物传感器的概述。(C)2010 Elsevier BV保留所有权利。
A sensitive monitoring of contaminants in food and environment, such as chemical compounds, toxins and pathogens, is essential to assess and avoid risks for both, human and environmental health. To accomplish this, there is a high need for sensitive, robust and cost-effective biosensors that make real time and in situ monitoring possible. Due to their high sensitivity, selectivity and versatility, affinity-based biosensors are interesting for monitoring contaminants in food and environment. Antibodies have long been the most popular affinity-based recognition elements, however recently a lot of research effort has been dedicated to the development of novel recognition elements with improved characteristics, like specificity, stability and cost-efficiency. This review discusses three of these innovative affinity-based recognition elements, namely, phages, nucleic acids and molecular imprinted polymers and gives an overview of biosensors for food and environmental applications where these novel affinity-based recognition elements are applied. (C) 2010 Elsevier B.V. All rights reserved.