The medial frontal cortex and temporal memory: tests using spontaneous exploratory behaviour in the rat
The medial frontal cortex and temporal memory: tests using spontaneous exploratory behaviour in the rat
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DOI：
10.1016/s0166-4328(98)00032-1
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发表时间：
1998-12-01
影响因子：
2.7
通讯作者：
Laiacona, J
中科院分区：
文献类型：
--
作者：
Mitchell, JB;Laiacona, J
来自几个来源的证据表明，额叶皮质参与了涉及时间的记忆或时间记忆，以及行为序列。大鼠被呈现给两个熟悉的物体，并记录针对每个物体的探索量。受试者将更多的探索指向过去遇到的更远的物体，即使两个物体只有1小时的差异。在双侧额叶内侧皮质损伤后，动物没有区分旧的和新的物体。同样使用探索时间的物体识别测试(新奇物体与熟悉物体)的性能没有因内侧额叶皮质损害而改变。(C)1998 Elsevier Science B.V.保留所有权利。
Evidence from several sources indicates that the frontal cortex is involved in memory involving time, or temporal memory, and in behavioral sequencing. Rats were presented with two familiar objects and the amount of exploration directed at each was recorded. Subjects directed more exploration at the object encountered further ago in the past, even though the two objects differed by only 1 h. After bilateral medial frontal cortex lesion, animals did not differentiate between old and recent objects. Performance on an object recognition test (novel versus familiar objects) that also used exploration time did not change as a result of the medial frontal cortex lesions. (C) 1998 Elsevier Science B.V. All rights reserved.