Monitoring of Atg5-Independent Mitophagy
Monitoring of Atg5-Independent Mitophagy
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Atg5 独立线粒体自噬的监测
DOI:
10.1007/7651_2017_16
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发表时间:
2017
期刊:
影响因子:
--
通讯作者:
Shimizu Shigeomi
中科院分区:
文献类型:
--
作者:
Arakawa Satoko;Honda Shinya;Torii Satoru;Tsujioka Masatsune;Shimizu Shigeomi
Mitophagy is a mitochondrial quality control mechanism where damaged and surplus mitochondria are removed by autophagy. There are at least two different mammalian autophagy pathways: the Atg5-dependent conventional pathway and an Atg5-independent alternative pathway; the latter is involved in the erythrocyte mitophagy. In this chapter we describe the various experimental approaches to assess Atg5-indepedndent mitophagy in mammalian cells.