Pregnancy outcomes in patients with pulmonary arterial hypertension A retrospective study
Pregnancy outcomes in patients with pulmonary arterial hypertension A retrospective study
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肺动脉高压患者妊娠结局的回顾性研究
DOI：
10.1097/md.0000000000020285
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发表时间：
2020-06-01
期刊：
影响因子：
1.6
通讯作者：
Li, Jiang
中科院分区：
文献类型：
--
作者：
Luo, Jun;Shi, Huafang;Li, Jiang
患有肺动脉高压（PAH）的孕妇的死亡率仍然很高。本研究回顾性分析79例妊娠合并肺动脉高压（PAH）流产或分娩患者的围生期及产后结局。本病例系列研究分析了术前特征、麻醉方法、重症监护管理、PAH特异性治疗以及母婴结局。我们收集了孕产妇、产科和新生儿结局的数据。轻度和重度PAH产妇的平均年龄分别为26.6 +/- 5.7和26.0 +/- 4.9岁，两组的平均肺动脉收缩压分别为43.8 +/- 4.2 mmHg和76.7 +/- 15.6 mmHg。79例患者中，43例（54.4%）为重度PAH，36例（45.6%）为轻度PAH。重度PAH组孕周明显短于轻度PAH组（36.0 vs 37.3周，6/24 vs 1/30; P
The mortality of pregnant women with pulmonary arterial hypertension (PAH) remains high. The aim of this study was to evaluate and analyze perinatal and postpartum outcomes in patients with PAH.A total of 79 pregnant patients with PAH who underwent abortion or parturition were reviewed retrospectively. Preoperative characteristics, anesthesia method, intensive care management, PAH-specific therapy, and maternal and neonatal outcomes were analyzed in this case series study.This study was a retrospective analysis of 79 pregnant women with PAH. We collected data on maternal, obstetrical, and neonatal outcomes. The mean age of the parturient women with mild and severe PAH was 26.6 +/- 5.7 and 26.0 +/- 4.9 years, respectively, and the mean systolic pulmonary arterial pressure of the 2 groups was 43.8 +/- 4.2 mmHg and 76.7 +/- 15.6 mmHg, respectively. Of the 79 patients, 43 (54.4%) had severe PAH and 36 (45.6%) had mild PAH. The gestational weeks were significantly shorter and the rate of fetal death was higher in the severe PAH group than in the mild PAH group (36.0 vs 37.3 weeks and 6/24 vs 1/30, respectively; P